Genome Guardian
COMBINE WEAPONS in the microscopic roguelite turret shooter with macroscopic depth. Survive 6 modes using an astounding array of turrets, perks, mutations and power-ups on this psychedelic journey to the heart of the abyss. Shmup Mode turns it into a vertical shoot 'em up!
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About
Dive into the microscopic world, radiating with bioluminescent life and unspeakable horrors. Genome Guardian is a deeply-complex shooter that's easy to pick up but hard to master. Research permanent upgrades to survive a variety of microbes across 6 game modes, each with multiple "depths".
Pair DNA nucleotides Adenine (rapidfire), Cytosine (precision), Guanine (spread), Thymine (explosive) to discover wild hybrid bioweapons!
Bomb + Shotgun combines explosives with spread to create Blast Shotgun!
Bomb + Bomb doubles down on explosive power to make Bazooka!
Blast Shotgun + Shotgun forms the all-powerful Flak Cannon!
49 Turrets with unique strengths and functions
96 Perks to mix and match that drastically change how you play
75 Weapon & Turret Mods that can turn shots into sticky laser mines or bouncing fireballs
64 Mutations alter the challenges you face each run
20-minute Runs that can be continued in Endless Mode
75 Bassy Electronic Tunes that adapt to the current mood & intensity
Cosmetics like spider legs and tank tread
Accessibility Settings for colourblindness, motion sickness, and even arachnophobia!
100 Steam Achievements
Steam Trading Cards
Cloud Save
Plays great on Steam Deck!!!
Facts
- Released
- Feb 6, 2025
- In catalog since
- Oct 18, 2026
- Publisher
- Stingbot Games
- Developer
- Stingbot Games, Inc.
- Platforms
- Switch, PC
- Genres
- Action, Casual, Indie, RPG
- Features
- Single-player, Steam Achievements, Full controller support, Steam Trading Cards, Camera Comfort, Color Alternatives, DualShock Controller Support, DualShock Controller Support, DualSense Controller Support, DualSense Controller Support, Steam Cloud, Family Sharing
- Languages
- English
System requirements
Minimum
Minimum:- OS: Windows 10
- Storage: 800 MB available space
- Additional Notes: Change Quality / Render Scale in SETTINGS if low FPS
Recommended
Recommended:- OS: Windows 10
- Storage: 800 MB available space
- Additional Notes: Change Quality / Render Scale in SETTINGS if low FPS











